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Article: Dysregulation of Kv3.4 channels in dorsal root ganglia following spinal cord injury.

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Ritter DM; Zemel BM; Hala TJ; O'Leary ME; Lepore AC; Covarrubias M
J. Neurosci., 2015


Table 2.

Kv3.4 current properties after laminectomy and SCI

Naïve 1 week 2 weeks 6 weeks
Lam SCI Lam SCI Lam SCI
Ip (pA) 40 ± 5 26 ± 3 37 ± 6 54 ± 10 46 ± 9 34 ± 6 28 ± 5
Ip/I500 4.7 ± 0.9 2.2 ± 0.4* 2.5 ± 0.3* 4.2 ± 0.8 2.4 ± 0.2* 3.2 ± 0.9 1.9 ± 0.4*
κ (s-1) 49 ± 6 33 ± 3 40 ± 2 57 ± 9 63 ± 13 51 ± 2 42 ± 6
N 18 21 18 27 30 13 20
  • Mean ± SEM of Kv3.4 current properties following laminectomy (Lam) and SCI. Asterisks indicate p < 0.05 compared with naïve and laminectomy controls (for direct comparisons see Fig. 5).


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